This function identifies druggable fusion partners from a given data frame of fusion genes. It uses a reference data bundle to append targeted drug annotations based on the specified primary site.
Usage
get_druggable_fusion_partner(
df = NULL,
partner = "5P",
ref_data = NULL,
variant_display = FALSE,
primary_site = "Lung"
)Arguments
- df
A data frame containing fusion gene information with columns "VAR_ID" and "FUSION_GENE_5P" or "FUSION_GENE_3P".
- partner
A character string indicating whether to analyze the 5' or 3 ' fusion partner. Default is "5P".
- ref_data
A list containing reference data, including drug annotations.
- variant_display
A logical value indicating whether to use variant-level drug annotations. Default is FALSE.
- primary_site
A character string specifying the primary site for drug annotation. Default is "Lung".