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Function that predicts MSI status based on fraction of indels among calls

Usage

predict_msi_status(
  variant_set,
  ref_data,
  msi_prediction_model,
  msi_prediction_dataset,
  target_size_mb,
  sample_name = "Test"
)

Arguments

variant_set

data frame with somatic mutations/indels

ref_data

PCGR reference data object

msi_prediction_model

statistical model for MSI prediction

msi_prediction_dataset

underlying dataset from TCGA used for development of statistical classifier

target_size_mb

size of targeted genomic region (coding)

sample_name

name of sample

Value

msi_data