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Version 1.8.1
- CIViC update (20241107)
- NCI Thesaurus update (24.10d)
Version 1.8.0
- CIViC update (20241102)
- NCI Thesaurus update (24.09e)
- OTP update (2024.09)
- Clean-up of code for ChEMBL drug mappings
- skip DGIdb cross-references - rely on OTP
Version 1.7.1
- CIViC update (20240826)
- added location of MET exon 14 skipping splice site (grch37 principal transcript)
Version 1.7.0
- CIViC update (20240807)
- NCI Thesaurus update (24.07e)
- MitelmanDB update (20240715)
- New dataset: DepMap (cell line) RNA fusion events
Version 1.6.10
- Fixed some erroneous drug classifications
- CIViC update (20240621)
- OTP update (2024.06)
Version 1.6.8 (June 7th 2024)
- NCI Thesaurus update (24.05d)
Version 1.6.7 (May 23rd 2024)
- NCI Thesaurus update (24.04e)
- CIViC update (20240523)
Version 1.6.4 (April 30th 2024)
- Improved clinical (tumor site) annotations of fusions from MitelmanDB
Version 1.6.3 (April 26th 2024)
Version 1.6.2 (April 12th 2024)
- NCI Thesaurus update (24.03d)
Version 1.6.1 (March 26th 2024)
- Open Targets Platform update (v2024.03)
Version 1.6.0 (March 9th 2024)
Version 1.5.9 (February 29th 2024)
Version 1.5.8 (February 6th 2024)
- NCI Thesaurus update (24.01e)
Version 1.5.7 (February 3rd 2024)
- Fixed buggy alias from PubChem
Version 1.5.6 (January 31st 2024)
- Refine possible values in
treatment_category
argument to get_drugs()
function
- Fix anti-androgen classification
- Fixed bug in alias type notation for copy numbers and expression biomarkers
- Filter noise and rank output in helper function
get_targeted_drugs
- Include variant primary name in biomarker variants
Version 1.5.0 (January 25th 2024)
- Considerable improvement of drug classifications (output column
atc_level3
), considering both targeted agents and chemotherapy
- argument
drug_targeted_agent
renamed to treatment_category
- helper function
get_on_off_label_drugs
renamed to get_targeted_drugs
Version 1.4.10 (January 17th 2024)
- Updated NCI Thesaurus (23.12d)
- Updated CIViC data (20240114)
- Revised manual drug classification (building upon ATC)
Version 1.4.8 (December 12th 2023)
- Updated NCI Thesaurus - 23.11d
- Updated CIViC data (20231212)
Version 1.4.8 (November 30th 2023)
- Updated OTP (v2023.12)
- Updated Mitelman database (20231016)
Version 1.4.7 (November 3rd 2023)
- Fixed corrupt biomarker literature data frame
Version 1.4.6 (October 18th 2023)
- Fixed metadata
- Fixed out-dated version descriptions (GH site)
- Do not exclude compounds with missing drug action type (platins etc.)
Version 1.4.5 (October 6th 2023)
- Updated NCI Thesaurus - 23.09d
- Updated CIViC data
- Added drug class (ATC) to
get_on_off_label_drugs()
Version 1.4.4 (September 1st 2023)
- Updated NCI Thesaurus - 23.08d
- Updated CIViC data
- Updated Mitelman database (20230803)
-
get_biomarkers()
now exported as a main function